Mitochondria's Dark Matter: Uncovering the Energy Crisis in Neurodegenerative Diseases For decades, scientists have been searching for a smoking gun to explain the cognitive decline that accompanies neurodegenerative diseases like Alzheimer's.
The conventional wisdom held that amyloid plaques and tau tangles were the primary culprits, but recent research has begun to chip away at this narrative.
A growing body of evidence suggests that energy production in neurons – specifically, the functioning of mitochondria – may be a crucial factor in disease progression.